American Cleanroom Systems
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About Us

American Cleanroom Systems® is a certified team of experts, specializing in the manufacturing and design of Class 100 to Class100,000 modular cleanrooms for a vast array of industries. For more than 40 years, American Cleanroom Systems has provided premium quality cleanroom services and customer service.

Our Team

  • 150+ years of cleanroom experience, built more than 500 cleanrooms.
  • Degrees: architecture, electrical engineering, biochemistry, and accounting.
  • Experience not just building cleanrooms but operating them.

Our Offering

  • Easy to work with.
  • Custom design and engineering for your specific needs.
  • Wide variety of design and material options.
  • In house manufacturing and installation for the highest quality.
  • Conform to ISO 146441-1 and FED STD 209E cleanroom standards.

Why American Cleanroom Systems®

Our Team

  • Alyson Yu
  • Ana Espinoza Ramos
  • Anthony Chien
  • Charlie Castaneda
  • Elizabeth Mahoney
  • Mimmi Rogers
  • Dan Hammond - Specialist Biotech/Pharma
  • Fred Hutchinson - Specialist Biotech/Pharma
  • John Ricci - Specialist Biotech/Pharma
  • Pedro Riley - Specialist Latin America
  • Ray Winkowski - Specialist Aerospace


American Cleanroom Systems® is the holder of a General Contractors license in the state of California. California, Class B – #979883. Washington State License: UBI#603 511 738. Arizona State License Class B-1 ROC323962. Iowa State License # C140110


  • 2020 CBD World Expo – “Cleanrooms for the CBD industry”
  • 2020 Del Mar Electronics and Manufacturing Show – “Cleanrooms in manufacturing”
  • 2020 Concentration – “Why you need a cleanroom for GMP CBD manufacturing”
  • 2021 Anaheim Manufacturing show – “How do cleanrooms work”
  • 2022 Del Mar Electronics and Manufacturing Show - Cleanrooms: Industrial, PCB, Semiconductor & other manufacturing applications

Proud to Support Our First Responders During COVID-19

Thank you to our COVID-19 first responders. American Cleanroom Systems donates 100 meals to the OC Sheriff Lake Forest station. Shout out to our friends at Chick-Fil-A for making the delicious food.

Our donation of 35 ChickFilA meals to the Boulder, CO fire department. Thank you to our first responders during Covid-19 from American Cleanroom Systems.

November 2020 – Operation Christmas Soldier. Our donation to gift backpacks for US Marines (Camp Pendleton).

September 24, 2020 – American Cleanroom Systems is proud to donate $250 to Ascension Sacred Heart Foundation to help Hurricane Sally victims in Pensacola Florida.

September 29, 2020 – American Cleanroom Systems donated Chick-Fil-A 25 meals to Chula Vista Police department as part of purchase a cleanroom and thank our local first responders program.

Proud to Support Our Local Community

July 2021 – Happy to provide breakfast to 75 Lion volunteers at free vision clinic

American Cleanroom Systems © is proud to sponsor

10U Lightning Bolts 2021 league champions!

Proud to sponsor the Moulton Elementary School PTA 2018 Boo Blast Fundraiser

2019 toy drive for kids of US Marine Corp 1st battalion 4th regiment Camp Pendleton

American Cleanroom Systems® is a proud sponsor of Laguna Niguel Softball and the Moulton Elementary School 2019 Jog-a-thon.

Proud to sponsor Pop Warner Football Santa Margarita Titans

American Cleanroom Systems

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23221 Arroyo Vista Rancho Santa Margarita California, 92688
Phone: 949.589.5656  
Fax: 949.589.6109
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