American Cleanroom Systems manufactures modular cleanrooms, cleanroom wall systems, doors, windows, ceilings, and related components at its factory in Rancho Santa Margarita, California. We provide design, manufacturing, installation, and cleanroom certification for ISO Class 4–8 environments and applications including pharmaceutical, medical device, semiconductor, aerospace, electronics, and R&D.
Made in USA – We manufacture our modular panels, doors, as well as our proprietary aluminum extrusions and ceiling. This allows us to ensure the highest quality while minimizing lead times.
Our current production line offers complete in-house laminating, product fabrication and assembly, and an array of automated equipment. Handling all your cleanroom needs is our advantage.
At American Cleanroom Systems, it’s our focus to provide you with the best product, service, and delivery to suit your goal. Proper equipment, financial strength, and a sound management approach assures you a quality project that is completed on schedule and on budget. All from a single source- American Cleanroom Systems®.
We are Avetta certified and Buy America Act compliant to ensure the highest quality of your modular cleanroom materials. We only use UL registered (or equivalent) electrical equipment and machinery in our cleanrooms.
Investing for the future of USA manufacturing. American Cleanroom Systems is proud to improve our manufacturing capabilities with a new Hendrick HM3 3200 Automatic Beam Saw and new Clark forklift. Clark manufactures its S-series forklifts in their Lexington Kentucky factory. Our Ford trucks are manufactured at Ford’s Dearborn Michigan factory.
What We Manufacture
American Cleanroom Systems manufactures modular cleanroom components at its California manufacturing facility, including:
- Modular cleanroom wall panels
- Cleanroom swing doors, motorized sliding, and motorized roll up doors.
- Cleanroom windows
- Proprietary aluminum wall extrusions
- Cleanroom ceiling systems
- Wall Pass Thrus
- Cart Pass Thrus
- HEPA filtered Pass Thru’s
- Softwall cleanrooms
- ISO-5 cleanroom bench
American Cleanroom Systems uses only Made in America cleanroom equipment in our cleanrooms.
- HEPA fan filter units
- Air showers
- Cleanroom flooring
- Clear vinyl strip curtains
- Humidifiers
- Dehumidifiers
- DX air-conditioning systems
- Magnehelic Gauges.
- Cleanroom Monitoring Systems
- De-ionizing systems
Why In-House Cleanroom Manufacturing Matters
Direct manufacturing control
American Cleanroom Systems manufactures in house all major cleanroom components at its California facility.
Custom dimensions
Factory fabrication allows panels, doors, windows, and openings to be produced to project-specific dimensions.
Less field fabrication
Electrical, data, return-air, and pass-through openings can be prepared before installation, reducing cutting and fabrication work at the job site.
Single-source project delivery
Design, manufacturing, installation, and testing can be handled by the same organization.
American Cleanroom Systems Manufacturing Capabilities
| Capability | American Cleanroom Systems |
| Manufacturing location | Rancho Santa Margarita, California |
| Manufacturing | In-house |
| Cleanroom types | Modular, softwall, hybrid |
| Cleanroom classifications | ISO class 4–8 and Fed Std 209E class 10–100,000 |
| Applications | Pharmaceutical, medical device, electronics, aerospace, semiconductor, biotech, industrial, universities and R&D laboratories. |
| Wall systems | Multiple skin and core configurations |
| Doors | Factory manufactured/custom sizes |
| Windows | Factory manufactured/custom sizes |
| Certification | ISO 14644-1 particle testing |
| Installation | Nationwide, Mexico, Central America, Latin America |
| Quote turnaround | 48 hours |
| USA manufacturing | 99% of cleanroom material made in USA |
Cleanroom Standards We Design and Manufacture For.
| Standard / requirement | Application |
| ISO 14644-1 | Cleanroom particle classification |
| FED-STD-209E | Legacy US cleanroom classification terminology |
| cGMP | Pharmaceutical/regulated manufacturing |
| USP 797 | Compounding environments |
| USP 800 | Hazardous drug handling |
| ISPE | Pharmaceutical facility design guidance |
| MIL-STD | Applicable military/aerospace requirements |
Industries American Cleanroom Systems manufacture cleanrooms for:
Pharmaceutical manufacturing
Medical device manufacturing
Semiconductor manufacturing
Electronics manufacturing
Aerospace
Biotechnology
Research and development labs
Optics
Precision manufacturing
3D printing
Food processing
Universities
Recent American Cleanroom Systems Projects
FAQs About Cleanroom Manufacturing
Q: How are modular cleanrooms manufactured?
A: Modular cleanroom is manufactured using prefabricated wall, ceiling, door, and other cleanroom components that are fabricated to the dimensions of the project and then assembled on-site. At American Cleanroom Systems, modular cleanroom manufacturing includes in-house panel laminating, fabrication, cutting, and assembly. Electrical and HVAC-related openings can also be prepared during manufacturing, reducing the amount of cutting and modification required during installation.
Q: Where are American Cleanroom Systems' cleanrooms manufactured?
A: American Cleanroom Systems manufactures modular and softwall cleanroom systems in the USA at its facility in Rancho Santa Margarita, California. The facility includes manufacturing operations, a design center, and a demonstration cleanroom, and customers can arrange a factory visit. 99% of modular cleanroom is made in USA – only significant exception is LED flat panel lights which are manufactured in Mexico.
Q: Where Do You Manufacture Your Cleanroom Doors and Cleanroom Windows?
A: Yes. American Cleanroom Systems modular cleanrooms are all manufactured to project-specific dimensions and configurations. Wall panels can be cut to required sizes, with factory-prepared openings for items such as return-air grilles, pass-throughs, make-up-air grilles, electrical outlets, light switches, and data connections. Custom cleanroom doors and windows are also manufactured at the company's California facility.
Q: What materials are used to manufacture cleanroom wall panels?
A: Cleanroom wall panels can be manufactured using different surface skins and core materials depending on the application. Available wall skins include melamine, FRP, painted aluminum, stainless steel, and vinyl gypsum board. Core options include honeycomb, aluminum honeycomb, polystyrene, urethane, and gypsum board. The appropriate combination depends on the cleanroom's application, performance requirements, and budget.
Q: How does factory manufacturing improve cleanroom installation?
A: Factory manufacturing allows components to be fabricated and prepared before they arrive at the project site. For example, wall panels are cut to their required dimensions and prepared for air grilles, pass-throughs, electrical connections, and data ports. This eliminates field cutting and fabrication, which can help shorten installation time and create a cleaner installation process.
Q: How do you ensure the cleanroom meets its required ISO classification?
A: After the cleanroom is completed and operating, American Cleanroom Systems performs an "as-built" particle test on each room. Testing is performed according to ISO 14644-1, and the company's laser particle counters are calibrated annually using NIST-traceable standards.
Q: Does American Cleanroom Systems have a quality program?
A: Yes. American Cleanroom Systems states maintains a written quality program and is Avetta certified. We have supplied our manufacturing quality plan to government and pharmaceutical organizations with demanding quality requirements.
Q: How is cleanroom manufacturing quality controlled?
A: Manufacturing quality is controlled through in-house fabrication, assembly, equipment maintenance, and testing. American Cleanroom Systems performs manufacturing at its California facility and conducts monthly, quarterly, and annual preventive maintenance on manufacturing equipment.
Q: How long does it take to manufacture a modular cleanroom?
A: Manufacturing and installation time varies according to cleanroom size, classification, configuration, equipment, and project requirements. Because many components are fabricated and prepared in the factory before installation, factory manufacturing can reduce the amount of fabrication required in the field. At American Cleanroom Systems upon approval of shop drawings manufacturing can take between 2 to 12 weeks.
Q: Can you manufacture cleanrooms for pharmaceutical and medical device applications?
A: Yes. American Cleanroom Systems manufactures cleanrooms for applications including pharmaceutical manufacturing, medical device manufacturing, electronics, aerospace, research, and other controlled-environment applications. The company also offers CGMP cleanroom systems and cleanroom testing and certification services.
Q: Do you manufacture softwall as well as hardwall cleanrooms?
A: Yes. American Cleanroom Systems manufactures both modular hardwall and softwall cleanroom systems. The company also offers hybrid cleanroom configurations and complete turnkey cleanroom systems.
Q: Can I visit your cleanroom manufacturing facility?
A: Yes. The Rancho Santa Margarita, California facility includes a demonstration cleanroom and design center, and customers are welcome to arrange a visit to the factory. Contact us at info@americancleanrooms.com or call 949-589-5656.
Q: Can American Cleanroom Systems handle the complete cleanroom project?
A: Yes. American Cleanroom Systems offers design, manufacturing, installation, and cleanroom testing/certification services. Turnkey systems can incorporate cleanroom construction, filtration, electrical systems, HVAC, flooring, and other project requirements.
Q: Can cleanroom wall panels be manufactured to custom dimensions?
A: Yes American Cleanroom Systems cleanroom panels can be cut in factory to customer dimensions.
Q: What ISO classifications can American Cleanroom Systems manufacture?
A: American Cleanroom Systems manufactures ISO-4 thru ISO-8 cleanrooms.
Q: Can you manufacture an ISO-5 cleanroom?
A: Yes. American Cleanroom Systems has manufactured ISO-5 cleanrooms.
Q: Can you manufacture an ISO-7 cleanroom?
A: Yes. American Cleanroom Systems has manufactured hundreds of ISO-7 modular cleanrooms.
Q: Can you manufacture an ISO-8 cleanroom?
A: Yes. American Cleanroom Systems has manufactured hundreds of ISO-8 modular cleanrooms.
Q: Does American Cleanroom Systems install the cleanroom after manufacturing it?
A: Yes, American Cleanroom Systems has factory installers that install cleanrooms nationwide.
Q: Can you manufacture pharmaceutical cleanrooms?
A: Yes American Cleanroom Systems manufactures pharmaceutical cleanrooms. Recent project 9,400 S.F. ISO-7 pharmaceutical cleanroom Texas.
Q: Can you manufacture medical device cleanrooms?
A: Yes, American Cleanroom Systems has manufactured hundreds of Medical device cleanrooms.
Q: Can you manufacture semiconductor cleanrooms?
A: Yes American Cleanroom Systems has manufactured semiconductor cleanrooms.
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