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All About Food Cleanrooms

December 18, 2022
Interior ISO7 cleanroom, stainless steel mixing equipment
Figure 1. Interior ISO7 gummy vitamins cleanroom

Cleanrooms are used in food and beverage manufacturing to conform with FDA CGMP regulations.

…“Following Current Good Manufacturing Practices (CGMPs) help to ensure the safety of food. CGMP regulations generally address matters including appropriate personal hygienic practices, design and construction of a food plant and maintenance of plant grounds, plant equipment, sanitary operations, facility sanitation, and production and process controls during the production of food." …

FDA CGMP logo
Figure 2. FDA CGMP Logo

https://www.fda.gov/food/guidance-regulation-food-and-dietary-supplements/current-good-manufacturing-practices-cgmps-food-and-dietary-supplements

The NSF is another standard for the food and beverage industry. The National Sanitation Foundation Institute is an organization that certifies food equipment that is designed and built in accordance with U.S. Food and Drug Administration (FDA) food safety and environmental health standards. Many beverages and food manufacturer conform to NSF standards.

National Sanitation Foundation logo
Figure 3. National Sanitation Foundation Institute logo

Cleanrooms are most common for beverage bottle filling operations but also for some food products. Since the bottles are often filled and sealed at elevated temperatures in moist steam filled environments, preventing contamination is very important.

Exterior ISO8 modular cleanroom, food ingredients, floor to ceiling cleanroom walls
Figure 4. Exterior ISO8 bottling food cleanroom

Typical Food Cleanroom Features Include:

  • Sloped heat welded vinyl floors with integral cove and floor drains are used to reduce moisture build up on the cleanroom floor that could encourage bacteria or mold growth. The heat welded vinyl floor is extremely durable and allows for vigorous regular chemical cleaning of the floor.
  • FRP or stainless steel cleanroom walls to allow regular chemical cleaning.
  • HVAC to control temperature and humidity in food cleanrooms.
  • Recessed HEPA filtration to prevent moisture from reaching HEPA filters
  • Conveyor openings in cleanroom walls
conveyor opening in cleanroom wall, conveyor
Figure 5. Conveyor opening food cleanroom
  • High bay ceilings for mixing tanks
high bay beverages modular cleanroom, glass cleanroom walls, workers
Figure 6. High bay mixing and bottling nutritional beverages cleanroom
  • Spill containment berms
  • Roll up doors for fork lifts material transfer
blue cleanroom motorized roll up door, interior ISO7 modular cleanroom
Figure 7. Cleanroom motorized Roll Up door
Property American Cleanroom Systems 2022

The author Anthony Chien has worked at American Cleanroom Systems for past 10 years. He has more than 40 years of cleanroom experience. Anthony has a BS and MS in Electrical Engineering specializing in semiconductor manufacturing from the University of Illinois. American Cleanroom Systems is a design build modular cleanroom manufacturer based in Rancho Santa Margarita CA. They are expert in ISO-5 thru ISO-8 (class 100 to class 100k) modular cleanrooms for pharmaceutical cleanrooms, medical device cleanrooms, food, nutraceutical and industrial cleanrooms.
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